RTx

• skin
• radiation dermatitis : erythema → dry/moist desquamation → ulceration 가능

• secondary malignancy : 수년~수십년 후 드물게

• 흉부 RTx

• radiation pneumonitis

  보통 RTx 이후 1-6개월 후

  dry cough, dyspnea, low grade fever, hypoxia

  CT 상 GGO, consolidation 형태

  D/Dx pneumonia, PE, CHF, cancer progression

• radiation pulmonary fibrosis

  보통 RTx 이후 6-12개월 후에 late change

  volume loss, bronchiectasis, restrictive pattern

• esophagitis

  치료중-수주 후

  dysphagia, chest discomfort

• pericarditis, valvular disease, cardiomyopathy

  특히 lt breast, mediastinal RT 시에 위험성 증가

• 두경부 RTx

• mucositis

  painful oral ulcer, swallowing difficulty

• xerostomia

  salivary gland dysfunction, chronic dry mouth

• laryngeal edema

  hoarseness, airway compromise

• hypothyroidism

  neck irradiation 후 흔한 late effect

• 복부/골반 RTx

• radiation enteritis

  acute = diarrhea, cramping , nausea

  chronic = malabsorption, stricture, fistula, bleeding, obstruction

• radiation proctitis

  tenesmus, urgency, rectal bleeding, pain

• radiation cystitis

  acute = frequency, urgency, dysuria

  chronic = hematuria, contracted bladder, ulceration, fistula

  D/Dx UTI, stone, tumor recurrence

• pelvic insufficiency fracture

• ovarian/testicular dysfunction

• CNS, spinarl cord RTx

• acute cerebral edema

  headache, nausea

• cognitive decline

• endocrine dysfunction

  pituitary/hypothalamus 영향 받는 경우

• breast RTx

• dermatitis

  breast edema, pain

• lymphedema

  axillary surgery, RT 병합 시 발병률 증가

• rib fracture, chest wall pain